Dystonia and akinesia due to pallidoputaminal lesions after disulfiram intoxication
Identifieur interne : 006181 ( Main/Exploration ); précédent : 006180; suivant : 006182Dystonia and akinesia due to pallidoputaminal lesions after disulfiram intoxication
Auteurs : Krauss [Allemagne] ; Mohsen Mohadjer [Allemagne] ; Ajay K. Wakhloo [Allemagne] ; Fritz Mundinger [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 1991.
English descriptors
- KwdEn :
- Adult, Akinesia, Alcoholism (rehabilitation), Basal ganglia, Disulfiram, Disulfiram (poisoning), Disulfiram (therapeutic use), Dose-Response Relationship, Drug, Drug Overdose (pathology), Dyskinesia, Drug-Induced (pathology), Dystonia, Dystonia (chemically induced), Dystonia (pathology), Female, Globus Pallidus (drug effects), Globus Pallidus (pathology), Humans, Magnetic Resonance Imaging, Neurologic Examination, Putamen (drug effects), Putamen (pathology), Suicide, Attempted, Tomography, X-Ray Computed.
- MESH :
- chemical , poisoning : Disulfiram.
- chemically induced : Dystonia.
- drug effects : Globus Pallidus, Putamen.
- pathology : Drug Overdose, Dyskinesia, Drug-Induced, Dystonia, Globus Pallidus, Putamen.
- rehabilitation : Alcoholism.
- chemical , therapeutic use : Disulfiram.
- Adult, Dose-Response Relationship, Drug, Female, Humans, Magnetic Resonance Imaging, Neurologic Examination, Suicide, Attempted, Tomography, X-Ray Computed.
Abstract
A case with segmental cranial plus crural dystonia of delayed onset and akinesia after acute intoxication with disulfiram is presented. Computed tomography showed bilateral pallidal lesions, whereas on magnetic resonance imaging aditional small lesions of the putamen could be detected. Long‐term observation with progression and a change of symptoms over a period of 10 years after the intoxication is demonstrated on videotape. Although other central side effects after intoxication with disulfiram are well known, movement disorders are uncommon. Carbon disulfide, a disulfiram metabolite, may be important in the etiopathogenesis.
Url:
DOI: 10.1002/mds.870060214
Affiliations:
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="1991">1991</date><biblScope unit="vol">6</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="166">166</biblScope><biblScope unit="page" to="170">170</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">84F902060F33869A9795C0195749A9B74C30A75A</idno><idno type="DOI">10.1002/mds.870060214</idno><idno type="ArticleID">MDS870060214</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Akinesia</term><term>Alcoholism (rehabilitation)</term><term>Basal ganglia</term><term>Disulfiram</term><term>Disulfiram (poisoning)</term><term>Disulfiram (therapeutic use)</term><term>Dose-Response Relationship, Drug</term><term>Drug Overdose (pathology)</term><term>Dyskinesia, Drug-Induced (pathology)</term><term>Dystonia</term><term>Dystonia (chemically induced)</term><term>Dystonia (pathology)</term><term>Female</term><term>Globus Pallidus (drug effects)</term><term>Globus Pallidus (pathology)</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Neurologic Examination</term><term>Putamen (drug effects)</term><term>Putamen (pathology)</term><term>Suicide, Attempted</term><term>Tomography, X-Ray Computed</term></keywords><keywords scheme="MESH" type="chemical" qualifier="poisoning" xml:lang="en"><term>Disulfiram</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Dystonia</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Globus Pallidus</term><term>Putamen</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Drug Overdose</term><term>Dyskinesia, Drug-Induced</term><term>Dystonia</term><term>Globus Pallidus</term><term>Putamen</term></keywords><keywords scheme="MESH" qualifier="rehabilitation" xml:lang="en"><term>Alcoholism</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Disulfiram</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Dose-Response Relationship, Drug</term><term>Female</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Neurologic Examination</term><term>Suicide, Attempted</term><term>Tomography, X-Ray Computed</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A case with segmental cranial plus crural dystonia of delayed onset and akinesia after acute intoxication with disulfiram is presented. Computed tomography showed bilateral pallidal lesions, whereas on magnetic resonance imaging aditional small lesions of the putamen could be detected. Long‐term observation with progression and a change of symptoms over a period of 10 years after the intoxication is demonstrated on videotape. Although other central side effects after intoxication with disulfiram are well known, movement disorders are uncommon. Carbon disulfide, a disulfiram metabolite, may be important in the etiopathogenesis.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Bade-Wurtemberg</li><li>District de Fribourg-en-Brisgau</li></region><settlement><li>Fribourg-en-Brisgau</li></settlement></list><tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Krauss" sort="Krauss" uniqKey="Krauss" last="Krauss">Krauss</name></region><name sortKey="Mohadjer, Mohsen" sort="Mohadjer, Mohsen" uniqKey="Mohadjer M" first="Mohsen" last="Mohadjer">Mohsen Mohadjer</name><name sortKey="Mundinger, Fritz" sort="Mundinger, Fritz" uniqKey="Mundinger F" first="Fritz" last="Mundinger">Fritz Mundinger</name><name sortKey="Wakhloo, Ajay K" sort="Wakhloo, Ajay K" uniqKey="Wakhloo A" first="Ajay K." last="Wakhloo">Ajay K. Wakhloo</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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